Package 'msigdbr'

Title: MSigDB Gene Sets for Multiple Organisms in a Tidy Data Format
Description: Provides the 'Molecular Signatures Database' (MSigDB) gene sets typically used with the 'Gene Set Enrichment Analysis' (GSEA) software (Subramanian et al. 2005 <doi:10.1073/pnas.0506580102>, Liberzon et al. 2015 <doi:10.1016/j.cels.2015.12.004>) in a standard R data frame with key-value pairs. The package includes the human genes as listed in MSigDB as well as the corresponding symbols and IDs for frequently studied model organisms such as mouse, rat, pig, fly, and yeast.
Authors: Igor Dolgalev [aut, cre]
Maintainer: Igor Dolgalev <[email protected]>
License: MIT + file LICENSE
Version: 7.5.1.9001
Built: 2024-08-13 03:17:26 UTC
Source: https://github.com/igordot/msigdbr

Help Index


Retrieve the gene sets data frame

Description

Retrieve a data frame of gene sets and their member genes. The available species and collections can be checked with msigdbr_species() and msigdbr_collections().

Usage

msigdbr(species = "Homo sapiens", category = NULL, subcategory = NULL)

Arguments

species

Species name, such as Homo sapiens or Mus musculus.

category

MSigDB collection abbreviation, such as H or C1.

subcategory

MSigDB sub-collection abbreviation, such as CGP or BP.

Value

A data frame of gene sets with one gene per row.

References

https://www.gsea-msigdb.org/gsea/msigdb/collections.jsp

Examples

# get all human gene sets

msigdbr(species = "Homo sapiens")


# get mouse C2 (curated) CGP (chemical and genetic perturbations) gene sets

msigdbr(species = "Mus musculus", category = "C2", subcategory = "CGP")

List the collections available in the msigdbr package

Description

List the collections available in the msigdbr package

Usage

msigdbr_collections()

Value

A data frame of the available collections.

Examples

msigdbr_collections()

List the species available in the msigdbr package

Description

This function is being deprecated and replaced by msigdbr_species().

Usage

msigdbr_show_species()

Value

A vector of possible species.


List the species available in the msigdbr package

Description

List the species available in the msigdbr package

Usage

msigdbr_species()

Value

A data frame of the available species.

Examples

msigdbr_species()